Senior Director, Toxicology Job at Revolution Medicines, Redwood City, CA

  • Revolution Medicines
  • Redwood City, CA

Job Description

Revolution Medicines seeks an experienced senior toxicologist to lead nonclinical safety strategy across its oncology drug portfolio. This role spans early research through clinical development, requiring scientific expertise in safety assessment and strategic cross-functional leadership within a collaborative R&D environment.

Responsibilities

  • Lead nonclinical safety strategy for multiple drug development programs in oncology
  • Design, oversee, and interpret toxicology studies supporting candidate selection and regulatory submissions
  • Author and review regulatory documents ensuring GLP and ICH compliance
  • Serve as toxicology representative on cross-functional R&D project teams
  • Lead nonclinical sub-teams, mentor colleagues, and drive mechanistic studies with emerging methodologies

Requirements

  • PhD in Toxicology or related field with 10+ years, or M.S. with 15+ years biopharmaceutical experience
  • Deep expertise in nonclinical safety assessment for small molecules and other modalities
  • Strong understanding of toxicology study design, GLP, and global regulatory requirements
  • Proven ability to lead cross-functional teams and influence development strategy
  • Excellent critical thinking and scientific communication across disciplines
  • DABT certification desirable

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